This guide contains information about places where you can stop for the night when driving from
Knoxville, Tennessee to Myrtle Beach, South Carolina.
Total distance for the trip is around 411 miles with a driving time of approximately 6 hours 22 mins.
Cities and towns with hotels that are on the fastest route between Knoxville and Myrtle Beach
are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)
115 miles from Knoxville (1 hour 50 mins)
305 miles from Myrtle Beach (4 hours 43 mins)
175 miles from Knoxville (2 hours 44 mins)
241 miles from Myrtle Beach (3 hours 50 mins)
263 miles from Knoxville (3 hours 57 mins)
153 miles from Myrtle Beach (2 hours 33 mins)
342 miles from Knoxville (5 hours 5 mins)
67.3 miles from Myrtle Beach (1 hour 19 mins)
